Evidence-based healthcare and the Cochrane Collaboration: An unfinished journey as yet! Commentary.

Objective: Although evidence-based medicine and the Cochrane Collaboration have become key players in modern medicine it is important to note that evidence-based medicine and the Cochrane Collaboration are confronted with a number of substantial challenges that need to be addressed. The aim of this work is to highlight some of these problems. Methods: This comment is based on a semi-structured literature review and my personal experience in the field of evidence-based medicine. Results: In this comment 3 important areas of controversy and conflict (“Improving the quality of Cochrane Review”; “Increasing the relevance to middle- and low-income countries”; and “Keeping reviews up to date”) will be highlighted and possible solutions will be presented. Conclusion:With the Cochrane Collaboration now having been at the forefront of promoting and implementing core principles of evidence-based medicine further organizational political and administrative efforts will have to be put in place to further improve the impact of evidence-based medicine in the field of health care. This process can best be realized through networking and cooperation of the medical community worldwide irrespective of geographic origin. When successfully tackling the above mentioned issues and obstacles the already amazing success story of evidence-based medicine and the Cochrane Collaboration will grow even more substantial.