Cannabis and cannabis withdrawal

Cannabis, or marijuana, has been the subject of much controversy. The authors discuss the neuropharmacology of tetrahydrocannabinol (THC). They relate the recent identification of a THC receptor site in the brain and its possible relevance to the existence of a marijuana withdrawal syndrome. Such a withdrawal syndrome is described. The authors conclude by presenting their views on legalization of marijuana. They are against legalization and present their case from a public health perspective.