Steady state pharmacokinetics of cycloserine in patients on terizidone for multidrug-resistant tuberculosis

Richard Court,Lubbe Wiesner,Annemie Stewart,N. De Vries,J Harding,Gary Maartens,Tawanda Gumbo,Helen McIlleron

Steady state pharmacokinetics of cycloserine in patients on terizidone for multidrug-resistant tuberculosis

2018

Richard Court
Lubbe Wiesner
Annemie Stewart
N. De Vries
J Harding
Gary Maartens
Tawanda Gumbo
Helen McIlleron

SUMMARY SETTING: Terizidone/cycloserine (TRD/CS) is included in standard treatment regimens for multidrug-resistant tuberculosis (MDR-TB) in many countries. The steady state pharmacokinetics (PKs) of CS after TRD administration are not known.

Keywords:

Immunology
Terizidone
Tuberculosis
Cycloserine
Multiple drug resistance
Medicine
Pharmacokinetics
Gastroenterology
Dosing
Standard treatment
Interquartile range
Internal medicine

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