Evaluation of the Potential Pharmacokinetic/Pharmacodynamic Interaction between Fluoxetine and Reboxetine in Healthy Volunteers

Objective: This study was performed to assess the tolerability of combined administration of reboxetine, a selective noradrenaline (norepinephrine) reuptake inhibitor, and fluoxetine, a selective serotonin reuptake inhibitor, relative to administration of each drug separately.