Nine acetylenic alcohols isolated from the Okinawan marine sponge of the genus Petrosia (Strongylophora).

Nine new acetylenic alcohols 1–9 were isolated from a marine sponge belonging to the genus Petrosia (Strongylophora). The structures were elucidated mainly based on the analysis of one-and two-dimensional NMR spectral data. To determine the position of the central double bonds in 1–8, each compound was cleaved with OsO4 and HIO4, and the resulting aldehyde was converted to the corresponding 2,4-dinitrophenylhydrazone. Analysis of the high-resolution mass and 13C NMR spectral data of each 2,4-dinitrophenylhydrazone clarified the position of the central double bonds in 1–8.