The range of neurological syndromes associated with glutamic acid decarboxylase antibodies

Neurological syndromes caused by production of antibodies to glutamic acid decarboxylase (GAD65) are a relatively new area of modern clinical neurology, which is of great theoretical and practical interest. High titer of identified antibodies is a not always specific, but highly sensitive, marker for autoimmune CNS disorders. The authors present their own clinical observations and an analysis of the literature on a wide phenotypic range of GAD65-associated pathologies.