NOVEL ANTIOXIDANTS FROM SAFFLOWER (CARTHAMUS TINCTORIUS L.) OIL CAKE

Three novel antioxidative serotonin derivatives were isolated from safflower oil cake (Carthamus tinctorius L.). Their structures were established as 4, 4"-bis(N-p-coumaroyl)serotonin (1), 4-[N-(p-coumaroyl)serotonin-4"-yl]-N-feruloyserotonin (2), and 4, 4"-bis(N-feruloyl)serotonin (3). Antioxidative activities of the compounds were measured by ferric thiocyanate method and DPPH method, and the compounds showed strong antioxidative activity.