Accelerated neuromodulation therapy for Obsessive-Compulsive Disorder.

Abbreviated Summary The open-label trial of Williams, Sudheimer, Cole, et al., suggests safety, feasibility, and high efficacy for treatment-refractory OCD of an accelerated, fMRI-guided, high-dose, cTBSmod protocol targeting the right frontal pole. Larger, randomized, controlled trials are needed to test the promising results of this pilot study. Clinicaltrials.gov Registry Numbers NCT03404609.