Bradycardia in a Neonate

The most important complication of neonatal lupus erythematosus (NLE) is congenital heart block (CHB) Infants with NLE are born to mothers who have antibodies against Ro (SSA) and/or La (SSB) antigens, although the mother may be completely asymptomatic Most children with CHB will eventually require a permanent pacemaker during childhood The risk of having a second baby with congenital heart block is within the range of 15–20%