Severity of Burn Injury and Sepsis Determines the Cytokine Responses of Bone Marrow Progenitor-Derived Macrophages

Background:Although thermal injury and sepsis result in enhanced monocytopoiesis, the functional characteristics of macrophages that develop in the microenvironment of burn and sepsis are unknown. Here we compare cytokine responses of bone marrow progenitor-derived macrophages (BMO) and peritoneal m