Preterm Prelabour Rupture of the Membrane & Feto-Maternal out come: an Observational Study

Summary: Objective: The aim of this study was to see the maternal andfetaloutcomeofpretermprelaborrupturemembrane and to identify the risk factors for preterm pre labor rupture membrane. Methods and Material: This was a cross-sectional descriptive type study carried out in Dhaka Medical College Hospital, Dhaka, duringApril to September, 2005 (6months) in the Department of Obstetric and Gynecology.50pregnantwomenwithpreterm premature rupture of the membrane (gestational age 29-0 to 36-6 weeks) were included in this study. Results:Themeanageofthewomenwas27.24±6.28years and 36% of them more than 30 years old. Sixty two percent women were multi gravid .Socio-economic condition, level of education and antenatal care of the womenwaslow.Mediangestationalageofthepatientwas 35weeks. Fifty six percent had previous history of PROM, preterm delivery, abortion, MR and dilatation and curettage. Sixty two percent women had history of sexual activity between 2 to 7days. Seventy two percent women had UTI, anaemia, and lower genital tract infection. Meandurationofthelatentperiodwas18.87±16.17hours and time interval of rupture membrane and delivery was 27.60 ± 21.127 hours. Eighty four percent patient deliveredbyvaginalrouteandFiftyfourpercentdelivered within24hoursofrupturedmembrane.Fortytwopercent newborn suffered from neonatal asphyxia, respiratory distress syndrome, neonatal jaundice and neonatal sepsis. Thirty two percent women suffered from chorioamnionitis, abruptio placent and endometritis. Conclusion: PPROM is malnutrition and poverty related disease .Antenatal care is an important tool to prevent PPROM by identifying the risk factors and its management.Steroidforfetallungmaturity,antibioticsto prevent fetal and maternal infection and induction and / oraugmentationoflaborwillspeededdeliveryandreduce hospital stay and infection. Key wards: Premature rupture of the membrane, maternal and neonatal outcome, risk factors. (J Bangladesh Coll Phys Surg 2010; 28: 17-23)