A Physiological Assessment of Patient Pain During Surgery with Wide-Awake Local Anesthesia

Abstract Purpose Patients receiving surgery with wide-awake local anesthesia typically report little or no intraoperative pain. However, self-report assessments are susceptible to bias. In the present study, patient self-report ratings were supplemented with objective physiological measures of electrodermal activity. Methods Fifteen patients receiving forefoot surgery using wide-awake local anesthesia were recruited. Pain ratings and skin conductance responses were acquired during the initial anesthetic injection (into unanesthetized tissue), during a follow-up anesthetic injection (into anesthetized tissue), and during five intraoperative procedures. Results The highest ratings of self-reported pain coincided with the initial anesthetic injection, and pain ratings were similarly low at all remaining measurement points. Fourteen patients reported no pain beyond the initial injection, whereas one patient reported minimal pain during two intraoperative procedures. Skin conductance data were consistent with pain ratings, such that responses to the initial injection were significantly larger than responses at any subsequent measurement point. Conclusion These results provide further evidence that patients experience little or no pain during surgery with wide-awake local anesthesia.