Combination of endoscopic tissue adhesive injection and variceal ligation in esophageal and gastric varices bleeding

Objective To evaluate the clinical efficacy of emergent endoscopic injection of tissue adhesive （N-oclyl-a-cyanoacrylate） combined with endoscopic variceal ligation （EVL） for esophageal and gastric wlrices bleeding. Methods Data of 21 patients with acute esophageal and gastric variees bleeding who received emergent endoscopic injection of tissue adhesive and EVL were retrospectively studied. Results The instant hemostatic rate was 95% （20/21） with no severe complications. Conclusion Emergent en- doscopic injection of tissue adhesive combined with EVL is an effective and safe therapy for esophageal and gastric varices bleeding. Key words: Esophageal varices ;  Gastric varices ;  Bleeding;  Tissue adhesives;  Cyanoacrylates