HLA-antigens in the Egyptian population

Abstract HLA-A, -B and -DR markers were determined for 380 normal unrelated Egyptians of both sexes. Typing for 9 A-locus, 15 B-locus and 6 DR-locus alleles was done. Antigen, gene and haplotype frequencies and Δ-values were estimated. The data obtained were statistically compared to those of Arabs at Gaza Strip, European and American Caucasians, American Blacks, African Blacks and Japanese (Orientals). The Egyptian genetic make-up was found to be heterogenous and some HLA markers differ significantly from that of other ethnic groups as well as Arabs from the Gaza Strip.