H-score of 11β-hydroxylase and aldosterone synthase in the histopathological diagnosis of adrenocortical tumors

Yi Yang,Ming Xiao,Ying Song,Yi Tang,Ting Luo,Shumin Yang,Wenwen He,Qingfeng Cheng,Linqiang Ma,Yao Zhang,Yunfeng He,Youde Cao,Jun Yang,Bin Peng,Jinbo Hu,Qifu Li

H-score of 11β-hydroxylase and aldosterone synthase in the histopathological diagnosis of adrenocortical tumors

2019

Yi Yang
Ming Xiao
Ying Song
Yi Tang
Ting Luo
Shumin Yang
Wenwen He
Qingfeng Cheng
Linqiang Ma
Yao Zhang
Yunfeng He
Youde Cao
Jun Yang
Bin Peng
Jinbo Hu
Qifu Li

Purpose To assess the diagnostic performance of the H-score of 11β-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) in the histopathological diagnosis of adrenocortical tumors (ACT).

Keywords:

Biology
Steroid 11-beta-hydroxylase
Endocrinology
Diabetes mellitus
Internal medicine
Aldosterone synthase
Pathology
Adrenocortical carcinoma
Immunohistochemistry
Receiver operating characteristic
Adenoma
Staining
Monoclonal antibody

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