PML hyposumoylation is responsible for the resistance of pancreatic cancer

Mirna Swayden,George Alzeeb,Rawand Masoud,Yolande Berthois,Stéphane Audebert,Luc Camoin,Laurent Hannouche,Hortense Vachon,Odile Gayet,Martin Bigonnet,Julie Roques,Françoise Silvy,Alice Carrier,Nelson Dusetti,Juan L. Iovanna,Philippe Soubeyran

PML hyposumoylation is responsible for the resistance of pancreatic cancer

2019

Mirna Swayden
George Alzeeb
Rawand Masoud
Yolande Berthois
Stéphane Audebert
Luc Camoin
Laurent Hannouche
Hortense Vachon
Odile Gayet
Martin Bigonnet
Julie Roques
Françoise Silvy
Alice Carrier
Nelson Dusetti
Juan L. Iovanna
Philippe Soubeyran

The dismal prognosis of pancreatic ductal adenocarcinoma (PDAC) is mainly due to its rapidly acquired resistance to all conventional treatments. Despite drug-specific mechanisms of resistance, none...

Keywords:

Diabetes mellitus
Cancer research
Promyelocytic leukemia protein
Posttranslational modification
Biology
Adenocarcinoma
SUMO protein
Internal medicine
Endocrinology
Pancreatic cancer
acquired resistance
pancreatic ductal adenocarcinoma

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