Chip Platforms and Chip Surface Treatments

There are three significant types of platforms used in microarray printing technology: glass slides, micropillar chips, and microwell chips. The surfaces of these platforms are treated for different applications. For example, a glass slide is ideal for micropatterning and can be used for microscopic image analysis. Micropillar and microwell chips are ideally suited for applications of high-throughput screening (HTS) of compounds on 3D-cultured cells. In this chapter, we present various methods by which these surfaces can be chemically modified for use in bioprinting applications, with emphasis on the methods used for culture of cells encapsulated in hydrogels.