Changes of coagulation parameters during stimulation in the IVF programme and in ovarian hyperstimulation syndrome

OBJECTIVE: Evaluation of changes in hemostasis system during the ovarian stimulation in IVF programme and in patients with severe form of ovarian hyperstimulation syndrome. DESIGN: Review article. SETTING: Unica, Institute for Reproductive Medicine, Brno. METHODS: Survey and discussion based on literature review. CONCLUSION: Activation of coagulation system during the ovarian stimulation and in the development of ovarian hyperstimulation syndrome is mentioned. The risk of thrombosis is increased if the patient is carrier of thrombophilic status.