Fluoreszenz-Markierung mittels Indocyanin-Grün bei der Sentinel-Lymphknoten-Exstirpation in der Dermatoonkologie Indocyanine green fluorescence-guided sentinel lymph node biopsy in dermato-oncology

Summary Background: Sentinel lymph node biopsy (SLNB) for cutaneous malignanciesusually carried out with radioactive nanocolloids (Tc-99m). The SLNE is contro-versially discussed internationally. This is especially given to the high false-negative rate up to 44 %. An alternative could be the fluorescent dye indocya-nine green (ICG). Material and Methods: We investigated the advantage of intraoperative fluores-cence detection of lymphatic vessels and SLN with a Near-Infrared (NIR) camerain comparison to conventional methods using preoperative lymphoscintigraphyand SPECT/CT in 22 patients with malignant melanoma. Results: A total of 61 SLNs were removed in 22 operative procedures. In 7 SLN(10.3 %; 7/68) the histopathological assessment could demonstrate a metastatic Fluoreszenz-Markierung mittels Indocyanin-Grun bei der Sentinel-Lymphknoten-Exstirpation in derDermatoonkologie Indocyanine green fluorescence-guided sentinel lymph node biopsy in dermato-oncology Ingo Stoffels 1 , Hannah von der Stuck , Christian Boy