Permanent His pacing guided by three-dimension mapping system

Objective To investigate the feasibility and effect of His bundle pacing (HBP) guided by three-dimension mapping system. Method Thirty patients underwent permanent His pacing through three-dimension mapping system were enrolled in this study. The average age of study group was 59.2 years, with 17 male patients. Factors including the whole procedure time, the X-ray exposure time, the lead parameters, the QRS duration before and after operation were analyzed by SPSS. Results The study group were divided into selective HBP (only capture His bundle) and non-selective HBP (capture both His bundle and Para-Hisian ventricular tissue) . The average whole procedure time of permanent His pacing guided by three-dimension mapping system was 113 min, with the X-ray exposure of selective HBP and non-selective HBP was (6.20±4.02) min and (5.30±4.59) min, respectively. The statistical analysis of X-ray exposure was no difference in two groups. The lead parameters was programmed in selective HBP group as followings: the average impedance was (666.5±81.00) Ω, the average sense was (3.30±0.63) mV, and the average threshold was (1.80±0.50) V, respectively. While in non-selective HBP group, the average impedance was (598.00±112.33) Ω, with the average sense (7.40±0.99) mV and the average threshold was (1.21±0.41) V. The P value of impedance, sense, and threshold between two groups was 0.065, < 0.05 and 0.003, respectively. The selective HBP group had higher threshold and lower sense than non-selective HBP group. Conclusion The permanent His pacing guided by three-dimension mapping system was feasible clinically in decreasing X-ray exposure time, and achieving perfect lead parameters. Key words: Bradycardia; His pacing; Three-dimension; Mapping; Pacemaker