Statistical analysis the development of breast cancer; influencing factors

The incidence of breast cancer in Romania is about 66.2/100,000 and the mortality around 22.1/100,000. The European Association for the Study of Obesity shows that the prevalence of the obesity is 10-25% for men and 10-30% for women. Data from literature sustain that the costs linked with breast cancer management are about 126 billion euro in 2009, 40% representing medical costs. Increasing of the survival and the prolongation of the time to progression is very important because it means there is a significant decrease inthe cost linked to: oncological medication, the hospitalization days, diagnosis investigation and also a prolongation of the time in wich the patient is integrated socio-economically and also in the family. An important indicator in this disease would be the years of potential life lost.. Material and methods: in this paper, we followed the evolution of 50 patients treated between January 2009 and December 2014 within “Elias” University Emergency Hospital. The above mentioned patients were monitored from diagnosis until the first imagistic documented progression. Several parameters were monitored, amongst which the body mass index, time to progression, age distribution, Ki 67 proliferation index and also the correlation between the parameters. Results: The body mass of the majority of the patients (22) was between 30 and 35 kg/m2, thus being considered obese. The average value of the time to progression for the monitored patients was 40,98 months, in concordance with the values found in literature. One particular aspect of the monitored patients was the high frequency of breast cancer within the group of patients under age of 50, followed by 45-50 group and the last was the 35-45 group. Conclusions: The excess of adipose tissue could represent a negative prognostic factor in the breast cancer progression. One important aspect is that this prognostic factor could be influenced by creating policies aimed at weight losing and healthy life-style. Breast cancer occurs predominantly with women within the 4-5 age decade, thus, the mortality and the morbidity generated by it determines the loss of many potential life years and a social-economic exclusion of the respective women.