Effect of Therapeutic Interventions on Spatiotemporal Gait Parameters in Adults with Neurological Disorders: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Objective(s) The objective is to quantify the changes in gait after therapeutic intervention in the adults with neurological disorders. Data Sources A keyword search was performed in four databases: PubMed, CINAHL, Scopus, and Web of Science (01/2000-12/2020). We performed the search algorithm including all possible combinations of keywords. Full text articles were searched further using forward/backward search. Study Selection Studies were thoroughly screened on the following inclusion criteria: Study design: Randomized Controlled trial (RCT); older adults aged >55 with a neurological disorder; therapeutic intervention; spatial and temporal gait characteristics; Language: English. Data Extraction A standardized data extraction form was used to collect the following methodological outcome variables from each of the included studies: author, year, population, age, sample size, spatiotemporal gait parameters such as cadence, step length, step width, double limb support. Data Synthesis We included 19 out of 35 studies in meta-analysis on adults with neurological disorders. All analysis used effect sizes and standard error; p 0.05), electrical stimulation (z=2.42, p 0.05) on step length. Further, physical activity has the largest effect on cadence in adults with PD (z=2.84, p Conclusions Sensory stimulation especially, auditory, and somatosensory stimulation while walking had largest effect on step length in adults with PD. We also found that conventional PT did better on spatial gait parameter relative to other physical activity interventions in adults with PD and stroke. Author(s) Disclosures There is nothing to disclose.