Development of a cure model for the estimation of long-term outcomes in patients with microsatellite instability(MSI)-high metastatic colorectal cancer (mCRC) receiving immune-checkpoint inhibitors (ICIs).

Filippo Pietrantonio,Gabriele Infante,Sara Lonardi,Francesca Corti,Rossana Intini,Massimiliano Salati,Elisabetta Fenocchio,Carmen Belli,Chiara Cremolini,Giovanni Fucà,Alessandra Anna Prete,Virginia Quarà,Paolo Manca,Andrea Spallanzani,Federica Morano,Maria Di Bartolomeo,Giuseppe Curigliano,Filippo de Braud,Vittorina Zagonel,Rosalba Miceli

Development of a cure model for the estimation of long-term outcomes in patients with microsatellite instability(MSI)-high metastatic colorectal cancer (mCRC) receiving immune-checkpoint inhibitors (ICIs).

2021

87Background: Anti-PD-(L)1-based therapy yielded unprecedented efficacy in patients with MSI-high mCRC. A relevant proportion of subjects may achieve long-term disease control when receiving ICIs, ...

Keywords:

Microsatellite instability
Oncology
Colorectal cancer
disease control
in patient
Internal medicine
long term outcomes
immune checkpoint inhibitors
Medicine

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