Green iodination of pyrazoles with iodine/hydrogen peroxide in water
2008
In this Letter, we describe a practical, green iodination of pyrazoles to form the corresponding 4-iodopyrazole derivatives. The reaction takes place in water, using only 0.5 equiv of iodine and 0.6 equiv of hydrogen peroxide, a system that generates water as the only reaction by-product.
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