Development of increased airway responsiveness in two nurses performing methacholine and histamine challenge tests.

Lundgren R, Soderberg M, Rosenhall L, Norrman E. Development of increased airway responsiveness in two nurses performing methacholine and histamine challenge tests. Two nurses who frequently examined patients with methacholine or histamine challenge tests developed increased airway responsiveness and symptoms of asthma. It is important to use a good system for evacuating the test aerosol during challenge tests.