Direct Monofluoromethylthiolation with S‐(Fluoromethyl) Benzenesulfonothioate

An electrophilic shelf-stable monofluoromethylthiolating reagent S-(fluoromethyl)benezene sulfonothioate 1 was developed. In the presence of a copper catalyst, reagent 1 coupled with a variety of aryl boronic acids to give the corresponding monofluoromethylthiolated arenes in high yields. In addition, addition of reagent 1 to alkyl alkenes in the presence of a silver catalyst gave alkyl monofluoromethylthioethers in high yields.