Spatio-temporal Image Correlation in Diagnosis of Ventricular Septal Defect in Second Trimester

Purpose:To explore the clinical value of spatio-temporal image correlation(STIC) in diagnosing ventricular septal defect in second trimester.Methods:Two thousand three hundred and twenty-six fetuses in second trimester(pregnant 21 weeks -28 weeks) were examined by routine echocardiography, and then with STIC.The difference of diagnosis between that made by routine echocardiography and by echocardiography with STIC was compared.Results:Of 2326 cases,fetal STIC imaging was failed in 35 cases.Of all the patients diagnosed as VSD,28 cases were diagnosed after birth.The fetal STIC imagings of them were success.Twenty cases were diagnosed by routine echocardiography(rate of sensitivity 71.4%),27 cases were by STIC(rate of sensitivity 96.4%).There was significant difference between the diagnosis rate made by routine echocardiography and STIC(p0.05).Conclusion:Second trimester is the ideal time for STIC imaging.STIC can provide more image information of VSD.It can improve the diagnosis rate of VSD. As a supplementary mean to routine echocardiography,it has important clinical significance.