Moving from 2D to 3D conformal radiotherapy (3DCRT) in locally advanced head and neck cancer: A dosimetric comparison

16530 Background: The aim of this study is to evaluate the dosimetric parameters of 3D CRT in head and neck tumors, to compare with hypothetical 2D plans, and to evaluate the acute toxicity. Methods: A total of 33 patients with median age of 62 years (range: 23–87 ) and with histologically proven head and neck cancer were consecutively treated with 3D CRT using a 6-field photon beam technique. 9 patients had supraglottic carcinoma, 5 - glottic carcinoma, 4- nasopharyngeal carcinoma, 4 - thyroid carcinoma, 2- oropharyngeal cancer, 3 - carcinoma of oral cavity, 1- carcinoma of hypopharynx, 1- maxillary sinus carcinoma, 3- unknown primary, 1- recurrent laryngeal carcinoma. 28 patients received concomitant chemotherapy and 13 were treated with neoadjuvant chemotherapy, 5 patients received postoperative radiotherapy and 28 received definitive radiotherapy. A comparative analysis of dose distributions and dose-volume histograms (DVH) between 2D and 3D plans for 11 patients with glottic and supraglottic carcinom...