Abstract 15012: Lactate Dehydrogenase B and Pyruvate Oxidation Associated With Carfilzomib-Related Cardiotoxicity in Multiple Myeloma Patients: A Multi-omics Study

Marwa Tantawy,Lakshmi Manasa Chekka,Timothy J. Garrett,Sonal Singh,Chintan Shah,Michael G. Fradley,Robert F. Cornell,Rachid Baz,Nida Waheed,David DeRemer,Lihui Yuan,Taimour Y. Langaee,Keith L. March,Carl J. Pepine,Jan S. Moreb,Yan Gong

Abstract 15012: Lactate Dehydrogenase B and Pyruvate Oxidation Associated With Carfilzomib-Related Cardiotoxicity in Multiple Myeloma Patients: A Multi-omics Study

2020

Marwa Tantawy
Lakshmi Manasa Chekka
Timothy J. Garrett
Sonal Singh
Chintan Shah
Michael G. Fradley
Robert F. Cornell
Rachid Baz
Nida Waheed
David DeRemer
Lihui Yuan
Taimour Y. Langaee
Keith L. March
Carl J. Pepine
Jan S. Moreb
Yan Gong

Introduction: Multiple Myeloma (MM) is the second most frequent hematologic cancer in the United States. Carfilzomib (CFZ), a proteasome inhibitor used to treat relapsed and refractory MM, has been...

Keywords:

Cancer research
Carfilzomib
Proteasome inhibitor
Medicine
Pyruvate decarboxylation
Refractory
Lactate dehydrogenase B
Cardiotoxicity
multi omics
Multiple myeloma

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