Parasite clearance, cure rate, post-treatment prophylaxis and safety of standard 3-day versus an extended 6-day treatment of artemether-lumefantrine and a single low-dose primaquine for uncomplicated Plasmodium falciparum malaria in Bagamoyo district, Tanzania– a randomized controlled trial.

Lwidiko E. Mhamilawa,Billy Ngasala,Ulrika Morris,Eliford Ngaimisi Kitabi,Rory Barnes,Aung Paing Soe,Bruno P. Mmbando,Anders Björkman,Andreas Mårtensson

Parasite clearance, cure rate, post-treatment prophylaxis and safety of standard 3-day versus an extended 6-day treatment of artemether-lumefantrine and a single low-dose primaquine for uncomplicated Plasmodium falciparum malaria in Bagamoyo district, Tanzania– a randomized controlled trial.

2020

Lwidiko E. Mhamilawa
Billy Ngasala
Ulrika Morris
Eliford Ngaimisi Kitabi
Rory Barnes
Aung Paing Soe
Bruno P. Mmbando
Anders Björkman
Andreas Mårtensson

Background:Artemisinin-based combination therapy (ACT) resistant Plasmodium falciparum represents an increasing threat to Africa. Extended ACT regimens from standard 3 to 6 days may represent a mea ...

Keywords:

Malaria
Combination therapy
Plasmodium falciparum
Internal medicine
Tanzania
Artemether/lumefantrine
Randomized controlled trial
Artemisinin
Primaquine
Medicine
Drug resistance
Biology
Immunology

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