What Is the Impact of Positive Margins in the Liver

In this chapter, we will discuss what is the impact of positive margin and the optimal width after hepatectomy for CRLM. Several clinicopathological factors have been found to be independent predictors of survival. Resection margin status and width have been historically an important prognostic factor. Yet, more recent studies have challenged the oncologic impact of close or microscopically positive (R1) resection. This is particularly important to understand, as this is one factor which is potentially under the control of the surgeon.