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gastric syphilis mimicking neoplasm a case report
2018
1. Abstract 1.1. Introduction: Gastric syphilis is a rare and challenging
diagnosis in clinical practice. Due to decreasing incidence of syphilis, the
encounterment with the diagnosis became exceptionally rare. Kaunas regional Biomedical Research Ethics
Committee approved the presentation of this
case report (protocol no. BEC-LSMUC(R )-26). 1.2. Case Presentation: A 46 -year -old Caucasian female
with a 3 months history of mild epigastric pain, followed by vomiting, weight
loss, and early satiety. The symptoms and findings of instrumental examinations
led to initial diagnosis of gastric cancer. Partial distal gastrectomy and D2
lymphadenectomy was performed and histological examination showed active
chronic gastritis with dense lymphocytic and plasmocytic infiltration -alterations
were in line the diagnosis of syphilis, which was further confirmed by
serological tests. 1.3. Conclusion: Epigastric pain, anorexia, vomiting,
weight loss, together with radiological, endoscopic and microscopic appearance
of gastric syphilis may easily be confused with gastric lymphoma or carcinoma.
Furthermore, endoscopic gastric biopsies show non-specific histological
alterations. We suggest that in all patients with gastric symptoms mimicking
neoplasm with nonspecific endoscopic or histological findings, VDRL and TPHA
tests should be performed. 2. Keywords: Gastric Syphilis;
Gastrectomy; Plasmocytic Infiltration
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