EXPERIMENTAL MODEL OF CFS: COGNITIVE, PHYSICAL AND METABOLIC CHARACTERISTICS OF PATHOLOGY DEVELOPMENT

In the present study, an analysis of cognitive, behavioral, and metabolic changes during the dynamics of the development of pathology was conducted under an experimental model of chronic fatigue syndrome (CFS). A decrease in physical and research activity of experimental animals indicated the development of fatigue and a depressed emotional state. An increase in the concentration of lactate was also showed, that may indicate a violation of the energy metabolism.