Grading of soft tissue sarcomas on fine-needle aspiration cytology smear.

In this present study we have attempted to grade soft tissue sarcomas on fine-needle aspiration cytology (FNAC) material and then subsequently correlated our findings on histology section. A total of 44 cases of primary soft tissue sarcomas (STS) were graded and correlated with the subsequent histopathology sections. FNAC successfully diagnosed 40 cases and four cases were reported as benign. There were 11 grade I, 32 grade II and one grade III cases on histopathology. Out of the 11 grade I cases, only three cases were graded correctly on cytology. On FNAC, 31 sarcomas were diagnosed correctly as grade II tumors and one case was under diagnosed as benign. There was a single case of grade III sarcoma on histopathology which was correctly diagnosed and graded on FNAC. In majority of the STS it is possible to grade on FNAC. Grade I STS is relatively difficult to grade than grade II STS. Diagn. Cytopathol. 2010. © 2009 Wiley-Liss, Inc.