Blink reflex excitability in patients with fibromyalgia syndrome

WCN 2013 No: 907 Topic: 36 — Other topics Compressed sensing technology could accelerate MRI at 7 T G. Zhang, G. Xiao, Z. Dai, S. Li, R. Wu. Shantou University Medical College, Shantou, China; Math and Applied Mathematics, Hanshan Normal University, Chaozhou, China Background: Compressed sensing is an innovative theory of signal acquisition and processing based on the areas of applied mathematics. It works by using the mathematical algorithm to make an appropriate domain transformation for the collected signals and changing them into sparse or compressible signals. Afterwards, gathering the compressed signals directly to reconstruct the original signals at speedy, fine quality by themethod of reconstruction algorithm. Due to its excellent temporal resolution advantages and satisfactory temporal resolution, compressed sensing has become a research hotspot in the field of medical imaging. Objective: Based on the compressed sensing image reconstruction algorithm, we aim to use less data to obtain high quality reconstructed images which is good to accelerate medical imaging speed and reduce the radiation. Material and methods: We firstly make a sparse representation of the image scanned at 7 T via a multiscale wavelet transform by using MATLAB. After being compressed, the retained energy is 99.29%, and the number of zeros is 93.73%. That is, by wavelet transformation, most coefficients are small though nearly all the image pixels have nonzero values. Then we use the histogram method of the original image and synthesized image and make sure that the step of compression is significant. Finally, we reconstruct the image by the way of sequential minimal optimization. Conclusion: This method will be significant to achieve rapid high quality imaging in MRI at 7 T and it can reduce the cost during processing, storage and transmission. doi:10.1016/j.jns.2013.07.2116 Abstract — WCN 2013 No: 888 Topic: 36 — Other topics Blink reflex excitability in patients with fibromyalgia syndrome WCN 2013 No: 888 Topic: 36 — Other topics Blink reflex excitability in patients with fibromyalgia syndrome M.U. Aluclu, A.D. Turhanoglu. Neurology Department, Dicle University, Diyarbakir, Turkey; Department of Physical Medicine and Rehabilitation, Mustafa Kemal University Hospital, Hatay, Turkey Objective: We aimed to investigate the blink reflex excitability in fibromyalgia syndrome. Subjects and methods: A total of 23 women with FMS and 14 healthy female controls were studied. Blink reflexes were elicited by electrical stimulation of the supra-orbital nerve. The stimuli were applied at first single stimulus and then paired stimulus by using ISIs by 100–600 ms. Electromyography signals were recorded from the right orbicularis oculi muscle. Results: There are significant differences between FMS and controls in responses obtained by paired stimulus at 200–400 ms. Responses of R2 obtained by ISI at 100–400 ms were smaller than those obtained by single stimulus in controls. This inhibition disappeared in response to paired stimulus by 500, 600 ISI in controls. Yet, in FMS patients, this expected inhibition only appeared for iR2 and cR2 obtained at 100 ms ISI and then did not appear at the paired stimulus at 200–400 ms ISIs. Conclusions: Lack of BR R2 response inhibition to paired stimulus by ISIs might be an electrophysiologic evidence that indicates central sensitization in FMS. doi:10.1016/j.jns.2013.07.2117 Abstract — WCN 2013 No: 881 Topic: 36 — Other topics Semantic abilities in children with dyslexia S.M. Golubovic, S. Tubin. Faculty of Special Education and Rehabilitation, University of Belgrade, Belgrade, Serbia The goal of this research was to deduct the frequency of dyslexia and achievement of children with dyslexia on the Test of Short-term Verbal Memory, Test of Dominant Lateralization, Triage Articulation Test, Semantic Test, and Test of Voice Analysis and Synthesis. Methodology: From a total of 280 children which were tested at the end of the second, third and fourth grade, with the analysis of handwriting (dictation, explanation of what was happening, transcription), 38 children (13.57%) were singled out with dysgraphia, from which 57.9% with dyslexia and 42.1% with motor dysgraphia. They are all tested with the Tridimensional Reading Test (Helen Sax), and for this sample it singled out 25 (8.9%) children with dyslexia. From the total number of dyslexic children, 88% have dyslexic dysgraphia, and the remaining 12% have graphomotor problems. Children with intellectual dispairment, bilingual children, as also socio-educationally ignored children, are excluded from the research. Results: The best results were shown on the test of metonymswherein 80% of children gave all the answers, and 20% were partially successful, which means, there were no unsuccessful children. There were no incompletely unsuccessful children on the test of homonyms, but 60% of children have given just 2 of the expected 4 answers. On the test of antonyms there were 44% unsuccessful children. The test of synonyms has especially bad results, because 48% of children didn't give any answer, and 24% of children have given just one answer, meaning, only 28% have done well in this part of the test. doi:10.1016/j.jns.2013.07.2118 Abstract — WCN 2013 No: 873 Topic: 36 — Other topics Determination of expression pattern of big-H3 gene in the process of regeneration in a model of zebrafish eye cryoinjury WCN 2013 No: 873 Topic: 36 — Other topics Determination of expression pattern of big-H3 gene in the process of regeneration in a model of zebrafish eye cryoinjury G. Ahmedova, F. Yunusov, G. Rakhimbaeva. Neurology, Tashkent Medical Academy, Tashkent, Uzbekistan Introduction:Humans have a rather limited capacity to regenerate after injury, while other vertebrates such as the zebrafish are capable of regenerating many anatomical structures. One of them is transforming growth factor beta induced regeneration (initially called BIGH3, BIG-H3), which signals have emerged as one of the components of the inductive process. Our investigation focused on the role of BIGH3 in the process of retinal regeneration in zebrafish after cryoinjury, wherein it was important to establish its pattern of expression. Materials and methods: ABTL wild type zebrafish strains of both sexes 10–14 months of age were bred in standard fish facility conditions. In total, 45 zebrafish were used for the investigation of the process of regeneration in the retina. 40 of them were subjected to cryoinjury. Postinjury measurements were grouped into the following periods: 1 day postinjury (dpi), 2 dpi, 3 dpi, 5 dpi, 7 dpi, 15 dpi, 21 dpi and 28 dpi. RNA from retina was obtained by using the TRIZOL reagent. RNA concentrations and purity were measured using UV-spectrophotometry. Equal amounts of RNA were reverse transcribed into cDNA using StrataScript reverse transcriptase. Quantitative RT-PCR was performed for each sample in duplicate, using β-actin primers as control. Results: Pronounced upregulation of the expression was observed at 5 dpi. At 7 dpi, BIGH3 expression reached the highest point as Abstracts / Journal of the Neurological Sciences 333 (2013) e579–e628 e607