Anticonvulsant activity of Mimosa pudica decoction.

Abstract The decoction of Mimosa pudica leaves given intraperitoneally at dose of 1000–4000 mg/kg protected mice against pentylentetrazol and strychnine-induced seizures. M. pudica had no effect against picrotoxin-induced seizures It also antagonized N -methyl- d -aspartate- induced turning behavior. These properties could explain its use in African traditional medicine.