Investigation of Gengnianpingtiao prescription combined with cognitive behavioral intervention on perimenopausal syndrome

Objective To investigate the effect of Gengnianpingtiao prescription combined with cognitive behavioral intervention on perimenopausal syndrome.Methods 150 cases of perimenopausal syndrome were randomly divided into two groups.75 cases in control group received Qiangli Naoqingsu tablets.75 cases in treatment group received Gengnianpingtiao prescription combined with cognitive behavioral intervention.The course was four weeks in two groups.The changes of effect and symptom score were observed.Results The cure rate and total effective rate in treatment group(28.00%,90.67%) was higher than that in control group(6.66%,84.00%,P0.05).The effect of treatment group was superior to that in control group.Symptom score(Unless memory impairment and loss of libido integral) after treatment was improved as compared with that before treatment in treatment group(P0.05,P0.01).Hot flashes integral,backache integral,depression points,chills points after treatment were better than those before treatment in control group(P0.05).Irritability integral,edema integral,chest tightness,integral and malaise integral in treatment group were improved significantly as compared with those in control group after treatment(P0.05,P0.01).Conclusion Gengnianpingtiao prescription combined with cognitive behavioral intervention has reliable curative effect on perimenopausal syndrome.