Diagnostic value of prostate specific antigen in women with polycystic ovary syndrome

Hyperandrogenism is an important indicator for diagnosis of polycystic ovary syndrome (PCOS). However, since Stein-Leventhal identified this condition in 1935, there has not been any objective or reliable test of hyperandrogenism. Prostate specific antigen (PSA) is closely associated with androgen levels in patients with PCOS.Therefore PSA may be a potential marker to diagnose PCOS. In this paper, the value of PSA in PCOS diagnosis is reviewed. Key words: Polycystic ovary syndrome (PCOS); Prostate specific antigen; Hyperandrogenism; Serum biomarkers