del(6q) in Multiple Myeloma

Prognosis (highly variable) is according to the staging and other parameters, of which are now the karyotypic findings: two distinct cytogenetic pattern have been reported, according to the chromosome number: 1a hyperdiploid pattern, and 2a pattern of either pseudodiploidy, hypodiploidy or near-tetraploidy karyotypes; patients with the latter pattern appear to have a worse prognosis than patients with a hyperdiploid karyotype (med survival of 1.5 yr vs 3 yrs; p<0.04). del(6q) abnormalities were more frequent in the second hypodiploid group.