One-pot syntheses of 6-mercaptopurines (6MP) from 4,5-diamino-6-chloro-pyrimidines☆
2004
Abstract A one-pot synthesis of 6-mercaptopurines from 4,5-diamino-6-chloro-pyrimidine, an aldehyde and elemental sulfur is presented. The key advantage of this procedure is that it utilizes the in situ generated H 2 S to convert the chloro to a mercapto group.
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