A new concept of continuous gemcitabine infusion: Fixed-dose-rate gemcitabine plus Platinum in metastatic transitional cancer –preliminary results of a phase I study

4641 Background: The intracellular accumulation rate of Gemcitabine (G) is saturated at a serum concentration of G of 15–20 micromol/l. A continuous infusion of 10 mg/m2/min achieves this level (26...