PHYSIOXIA-PRECONDITIONED MESENCHYMAL STEM CELLS IMPROVE CARTILAGE REGENERATION FOR THE TREATMENT OF EARLY OSTEOARTHRITIS DEFECTS

Osteoarthritis (OA) is a progressive and degenerative joint disease resulting in changes to articular cartilage. In focal early OA defects, autologous chondrocyte implantation (ACI) has a 2-fold fa...