Abstract 20561: Detecting Pre-Clinical Pro-Arrhythmia Risk in vitro Using Mature Human Induced Pluripotent Stem Cell Derived Cardiomyocyte Monolayers in a Quantitative Electrophysiological High Content Screen

Katherine Campbell,André Monteiro da Rocha,Sergey Mironov,Jiang Jiang,José Jalife,Todd J. Herron

Abstract 20561: Detecting Pre-Clinical Pro-Arrhythmia Risk in vitro Using Mature Human Induced Pluripotent Stem Cell Derived Cardiomyocyte Monolayers in a Quantitative Electrophysiological High Content Screen

2017

Katherine Campbell
André Monteiro da Rocha
Sergey Mironov
Jiang Jiang
José Jalife
Todd J. Herron

Introduction: Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) offer a novel in vitro platform for pre-clinical cardiotoxicity and pro-arrhythmia screening of drugs in develop...

Keywords:

Cardiotoxicity
Internal medicine
Induced pluripotent stem cell
Pharmacology
Electrophysiology
Cardiology
Medicine
In vitro
stem cell biology
Cancer research

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