Reliability and validity of the Japanese version of the Ocular Surface Disease Index for dry eye disease

Objectives The Ocular Surface Disease Index (OSDI) questionnaire is widely used to evaluate subjective symptoms of dry eye disease (DED) as a primary diagnostic criterion. This study aimed to develop a Japanese version of the OSDI (J-OSDI) and assess its reliability and validity. Design and setting Hospital-based cross-sectional observational study. Participants A total of 209 patients recruited from the Department of Ophthalmology at Juntendo University Hospital. Methods We translated and culturally adapted the OSDI into Japanese. The J-OSDI was then assessed for internal consistency, reliability and validity. We also evaluated the optimal cut-off value to suspect DED using an area under the receiver operating characteristic curve (AUC) analysis. Primary outcome measures Internal consistency, test–retest reliability and discriminant validity of the J-OSDI as well as the optimal cut-off value to suspect DED. Results Of the participants, 152 had DED and 57 did not. The J-OSDI total score showed good internal consistency (Cronbach9s alpha=0.884), test–retest reliability (interclass correlation coefficient=0.910) and discriminant validity by known-group comparisons (non-DED, 19.4±16.0; DED, 37.7±22.2; p Conclusions The J-OSDI was developed and validated in terms of reliability and validity as an effective tool for DED assessment and monitoring in the Japanese population.