Associated arterial and venous cerebral manifestations in Behçet's disease

Abstract Behcet's disease is a rare multisystemic vasculitis with an etiology that is still unknown. Neurological manifestations may be seen in approximately 5–15% of patients, and both parenchymal and extraparenchymal neurological involvement has been described. When cerebral venous thrombosis (CVT) is the main extraparenchymal manifestation of Behcet's disease, the condition is then dubbed “angio-Behcet's syndrome”. However, arterial involvement is extremely rare, with only one reported case of vasculo-neuro-Behcet's disease, characterized by both venous and intracranial arterial involvement – until now. This report is of two patients diagnosed with Behcet's disease characterized by the concomitant presence of both cerebral arterial manifestations and CVT.