Study on the difference of drug-nature of Fructus Evodiae Rutaecarpae processed Coptis chinensis based on laboratory animals praxiology

Objective: Study on the difference of drug-nature of Fructus Evodiae Rutaecarpae processed Coptis chinensis based on praxiology of laboratory animals.Methods:KM mice was adopted,and they were administed Rhizoma Coptidis,Fructus Evodiae Rutaecarpae,and Fructus Evodiae Rutaecarpae processed Coptis chinensis,respectively.Temperature tendency,vitality of ATP enzyme in liver were determinated to research the different effects of different drugs to energy metabolism.Results: All the mice in Fructus Evodiae Rutaecarpae group incarnated ' cold tendency',and the vitality of ATP enzyme increased.All mice in Rhizoma Coptidis and Fructus Evodiae Rutaecarpae processed Coptis chiensis group incarnated ' hot tendency',and the vitality of ATP enzyme depressed.Otherwise,the 'hot tendency' in Rhizoma Coptidis group was higher than its in Fructus Evodiae Rutaecarpae processed Coptis chiensis group(P0.05),and the vitality of ATP enzyme in Rhizoma Coptidis group was lower than its in Fructus Evodiae Rutaecarpae processed Coptis chiensis group(P0.05).Conclusion: Fructus Evodiae Rutaecarpae manifested the 'hot nature',Rhizoma Coptidis and Fructus Evodiae Rutaecarpae processed Coptis chinensis manifested the 'cold nature',but the 'cold nature'of Fructus Evodiae Rutaecarpae processed Coptis chinensis is lower than Coptis chinensis.This conclusion is consistent with traditional Chinese Medicine theory.