Inhibitory effects of synthetic histidine-rich peptides on haemagglutination by Bacteroides gingivalis 381.

Abstract The haemagglutinating activity of Bacteroides gingivalis 381 was significantly inhibited by the synthetic peptide, Asp-Ser-His-Ala-Lys-Arg-His-His-Gly-Tyr-Lys-Arg-Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr. However, bradykinin potentiator C, which does not contain cationic amino acids such as l -histidine, l -arginine and l -lysine, had no inhibitory effect.