Activity of 17β‐hydroxysteroid dehydrogenase in various tissues of human skin

SUMMARY The activity of 17β-hydroxysteroid dehydrogenase (17β-HSD) was assayed in various tissues microdissected from the freeze-dried human skin of fourteen subjects. The apocrine sweat gland, sebaceous gland and hair follicle possessed a high activity of 17β-HSD. The enzyme activity was negligible in the epidermis, except that the scalp epidermis showed much the same activity as the hair follicle. The dermis showed variable activity because of contamination with other components.