Heparan Sulfate-Editing Extracellular Sulfatases Enhance Vascular Endothelial Growth Factor Bioavailability for Ischemic Heart Repair

Mortimer Korf-Klingebiel,Marc R. Reboll,Karsten Grote,Hauke Schleiner,Yong Wang,Xuekun Wu,Stefanie Klede,Yuliya Mikhed,Johann Bauersachs,Michael Klintschar,Carsten Rudat,Andreas Kispert,Hans W.M. Niessen,Torben Lübke,Thomas Dierks,Kai C. Wollert

Heparan Sulfate-Editing Extracellular Sulfatases Enhance Vascular Endothelial Growth Factor Bioavailability for Ischemic Heart Repair

2019

Mortimer Korf-Klingebiel
Marc R. Reboll
Karsten Grote
Hauke Schleiner
Yong Wang
Xuekun Wu
Stefanie Klede
Yuliya Mikhed
Johann Bauersachs
Michael Klintschar
Carsten Rudat
Andreas Kispert
Hans W.M. Niessen
Torben Lübke
Thomas Dierks
Kai C. Wollert

Rationale: Mechanistic insight into the inflammatory response after acute myocardial infarction (MI) may inform new molecularly-targeted treatment strategies to prevent chronic heart failure. Objec...

Keywords:

Internal medicine
Sulfatase
Heart failure
Bioavailability
Diabetes mellitus
Vascular endothelial growth factor
Cardiology
Biology
Extracellular
Pharmacology
Heparan sulfate
Myocardial infarction
Inflammation
Cancer research
Vascular endothelial growth factor A
Bone marrow
Angiogenesis
SULF1

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