The Factors Improve Peak Oxygen Consumption are Different between Heart Failure with Reduced Ejection Fraction and with Preserved Ejection Fraction

one month after IR. Result: LVAD+VNS normalized LV end-systolic elastance and decreased LV end-diastolic pressure (EDP) (IR: 14.666.7, VAD: 6.461.5, VAD+VNS: 3.760.4 mmHg, p!0.05), indicating that VAD+VNS fully preserved LV function. NT-proBNP paralleled LVEDP. VAD+VNS strikingly reduced the infarct size (IR: 11.663.1, VAD: 8.762.9, VAD+VNS: 2.960.6%, p!0.05). Conclusions: The combination of VAD with VNS markedly reduces the infarct size and prevents CHF in one month after IR. This treatment would improve the long term mortality resulting from post-infarct chronic heart failure in patients.